Is the symptom severity worse in wet-OAB than dry-OAB of female patients in a real-life clinical practice?
Professor Dong Hwan Lee (1), Professor Hyun Woo Kim, Professor Joon Chul Kim, Professor Jong Bo Choi, Professor Jung Jun Kim
(1) Department Of Urology, Incheon St. Mary's Hospital, The Catholic University Of Korea, South Korea, (2) Department of Urology, Eun Pyeong St. Mary's Hospital, The Catholic University of Korea, (3) Department of Urology, Bucheon St. Mary’s Hospital, The Catholic University of Korea, (4) Department of Urology, Ajou University Hospital, Ajou University, (5) Department of Urology, Incheon St. Mary’s Hospital, The Catholic University of Korea
Wetting has been considered as one of the representative symptoms worsen the quality of life (QoL) in overactive bladder (OAB) patients. The severity regarding QoL of wet-OAB was evaluated and compared with dry-OAB in female patients.
Female OAB patients defined with 3 or more urgency scale measured by overactive bladder symptom score (OABSS) were enrolled for this cross-sectional study. Patients were divided into two groups; wet-OAB when episode of urge incontinence was one or more per week and dry-OAB less than one episode. The primary endpoint was QoL assessed by Patient Perception of Bladder Condition (PPBC), and the objective voiding profile was assessed by voiding diary for 3 days. The secondary endpoint was the differences in OABSS, International Consultation on Incontinence Questionnaire-OAB (ICIQ-OAB) and OAB questionnaire-short form (OABq-SF) between two groups.
Total 70 female patients were enrolled as OAB, 33 (47.1%) were dry- and 37 (52.9%) were wet-OAB. The median age of wet-OAB (61.6±11.5) was older than dry-OAB (55.6±10.1). The QoL assessed by PPBC was similar between two groups. Regarding voiding diary, 24-hour and daytime urinary frequency were severe and average voided volume was smaller in dry-OAB than wet-OAB (12.9±6.6 vs 9.8±3.5 and 131.8±56.1 vs 165.7± 43.8). The functional bladder capacity was similar between tgwo groups. Regarding subjective symptom score, both OABSS and ICIQ-OAB were also more severe in dry- than wet-OAB. The profile of ICIQ-OAB inconvenience score, OAB-q symptom score and OAB-QoL score were similar between two groups(see table).
Older age was a risk factor of wet-OAB. The general QoL of female wet-OAB was not worse than dry-OAB. Rather, some parameters of dry-OAB was worse than wet-OAB. Clinician should be aware of the underestimation of dry- than wet-OAB.